Additives / adulterants are chemicals
added to urine to try to mask the drugs in the
urine sample.
All adulterants are detectable.
Drug testing laboratories can find
anything that you have added to your urine sample.
Additive users may get lucky because some labs do not
test every urine sample for adulterants. Risking your
future on an unknown laboratory procedures is playing Russian
roulette.
Read the research below to learn
more.
| Clin Chem 1999 Jul;45(7):1051-7 |
|
Adulteration of urine by
"Urine Luck".
Wu AH, Bristol B, Sexton K, Cassella-McLane G,
Holtman V, Hill DW
Department of Pathology and Laboratory Medicine,
Toxicology Laboratory, Hartford Hospital, 80 Seymour
St., Hartford, CT 06102, USA.
BACKGROUND: In vitro adulterants are used to
invalidate assays for urine drugs of abuse. The
present study examined the effect of pyridinium
chlorochromate (PCC) found in the product
"Urine Luck". METHODS: PCC was prepared
and added to positive urine controls at
concentrations of 0, 10, 50, and 100 g/L. The
controls were assayed for methamphetamine,
benzoylecgonine (BE), codeine and morphine,
tetrahydrocannabinol (THC), and phencyclidine (PCP)
with the Emit II (Syva) and Abuscreen Online (Roche)
immunoassays, and by gas chromatography/mass
spectrometry (GC/MS).
-
- Two tests were also developed to
detect PCC in urine: a spot test to detect chromate
ions using 10 g/L 1,5-diphenylcarbazide as the
indicator, and a GC/MS assay for pyridine.
-
- The PCC did not affect the GC/MS
recovery of methamphetamine, BE, PCP, or their
deuterated internal standards.
-
- Identification of PCC use can be
accomplished with use of a spot test for the
oxidant.
|
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