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Effect of orange juice consumption
on urinary pH.
Embil K, Litwiller DC, Lepore RA, Field FP, Torosian
G
The effect of orange juice consumption on urinary pH was
studied in seven adult male subjects, each of whom
served as his own control. The diet of the subjects was
standardized during the work-day. The effects of two
regimens of orange juice were studied: 1500 ml divided
into five 300-ml portions during the day, and 300 ml
once in the morning. Urine was collected, its pH
recorded, and titrated with HCl to determine the mEq of
base excreted per unit time. The consumption of 300 ml
of orange juice did not significantly alter urinary pH.
The consumption of 1500 of orange juice changed the
urinary pH by an average of one pH unit. A change of
this magnitude could cause clinically significant
variation in the overall excretion pattern of acidic or
basic drugs.
PMID: 11688, UI: 77063192
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